Concepedia

Mode of action of the positive modulator PNU-120596 on α7 nicotinic acetylcholine receptors

Anett K. Szabo, Krisztina Pesti, Árpád Mike, E. Sylvester Vizi

Neuropharmacology · 2014 · 23 citations · 25 references

DOI

Concepts

References

25

A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor:<i>In Vitro</i>and<i>In Vivo</i>Characterization

Raymond S Hurst, Mihály Hajós, M. Raggenbass et al. · Journal of Neuroscience · 2005 · 444 citations · Full text

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Distinct Profiles of α7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes

Jens Halvard Grønlien, Monika Håkerud, Hilde Ween et al. · Molecular Pharmacology · 2007 · 272 citations

, , +17

Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Gareth T. Young, Ruud Zwart, Alison Walker et al. · Proceedings of the National Academy of Sciences · 2008 · 263 citations · Full text

, , +17

Choline and acetylcholine have similar kinetic properties of activation and desensitization on the α7 nicotinic receptors in rat hippocampal neurons

Árpád Mike, Newton G. Castro, Edson X. Albuquerque · Brain Research · 2000 · 131 citations

, , +16

The Interface between Extracellular and Transmembrane Domains of Homomeric Cys-Loop Receptors Governs Open-Channel Lifetime and Rate of Desensitization

Cecilia Bouzat, Mariana Bartos, Jeremías Corradi et al. · Journal of Neuroscience · 2008 · 123 citations · Full text

, , +17