Surgical Innovation · 2011 · 249 citations · 35 references
Veterinary MedicineSurgeryReconstructive SurgeryTissue EngineeringWound HealingNegative Pressure Wound TherapySurgical Wound HealingWound ClosureWound ManagementBiomechanical LoadingBiomechanical MechanismsClosed Incision Negative Pressure TherapyClosure Of IncisionsFinite Element ModelingFinite Element SimulationIncisional Negative Pressure Wound TherapyWound Closure Mechanics
A novel closed incision management with negative pressure wound therapy (CIM) has been developed for convenient use with closed incisions that has the potential to be beneficial for patients at risk for postoperative complications. Incisions are typically under lateral tension. This study explored the biomechanical mechanisms by which integrity of the incisional closure is enhanced by CIM. CIM was hypothesized to affect local stresses around closed incisions in a beneficial manner. Finite element analyses (FEA) indicated that application of CIM decreased the lateral stresses ~50% around the incision and changed the direction of the stresses to a distribution that is typical of intact tissue. Bench evaluations corroborated findings that CIM significantly increased the force required to disrupt the closed incision by ~50% as compared with closure alone. In conclusion, using 2 FEAs and bench modeling, CIM was shown to reduce and normalize tissue stresses and bolster appositional forces at the incision.
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Physiology, Biochemistry, and Molecular Biology of the Skin
Walter B. Shelley · JAMA · 1992 · 792 citations
Medicine, Anatomy, Physiology +15