Localization of Cacna1s to ON Bipolar Dendritic Tips Requires mGluR6-Related Cascade Elements

Abstract

Our results show that the localization and stability of Cacna1s depend on the expression of mGluR6 and its cascade components, and they suggest that Cacna1s is part of the mGluR6 complex. We hypothesize that Cacna1s contributes to light adaptation by permeating calcium.