Normal Brain Maturation Characterized With Age-Related T2 Relaxation Times: An Attempt to Develop a Quantitative Imaging Measure for Clinical Use

Abstract

T2 relaxation time correlates well with the progress of brain maturation. The used biexponential function reflects the dynamic development of myelination in newborns and young children as well as the maturation of myelination during adolescence and could be used to develop a "normal" reference for neuroradiological diagnoses.