Studies on the metabolic products of Aspergillus terreus. III. Metabolites of the strain IFO 8835. 1.

Abstract

A new type metabolite (I) was isolated from Aspergillus terreus var. africanus IFO 8835 together with terrein, 3, 6-dihydroxytoluquinone, emodin, questin, sulochrin, dihydroerdin, geodin, asterric acid, and aspulvinone D. The structure of I was determined as α-oxo-β-(p-hydroxyphenyl)-γ-(p-hydroxy-m-3, 3-dimethylallylbenzyl)-γ-methoxycarbonyl-γ-butyro-lactone by chemical and physical experimental data. Compound I was biosynthesized by intact condensation of two phenylpropanoids between carbons 2 and 3'.