Treatment of Mammary Carcinomas in HER-2 Transgenic Mice through Combination of Genetic Vaccine and an Agonist of Toll-Like Receptor 9 - Concepedia

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Treatment of Mammary Carcinomas in HER-2 Transgenic Mice through Combination of Genetic Vaccine and an Agonist of Toll-Like Receptor 9

47

Citations

40

References

2009

Year

Luigi Aurisicchio, Daniela Peruzzi, Antonella Conforti, Sridhar Dharmapuri, Antonella Biondo, Saverio Giampaoli, Arthur Fridman, Ansu Bagchi, Christopher T. Winkelmann, Raymond E. Gibson,

Clinical Cancer Research

Abstract

The combination of HER-2/neu genetic vaccine and novel agonist of TLR9 had potent antitumor activity associated with antibody isotype switch and antibody-dependent cellular cytotoxicity activities. These results support possible clinical trials of the combination of DNA-EP/Ad-based cancer vaccines and IMO.

References

	Year	Citations

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