Structures of the artabsinolides; photo-oxygenation studies on artabsin

Abstract

The structure and stereochemistry of four new guaianolides from Artemisia absinthium, named artabsinolides A, B, C, and D, have been established. They were synthesized via rearrangement or reduction of the endo-peroxides resulting from dye-sensitized photo-oxygenation of the main constituent of the plant, artabsin (1).