Increased Chemerin and Decreased Omentin-1 Levels in Morbidly Obese Patients are Correlated with Insulin Resistance, Oxidative Stress and Chronic Inflammation

Abstract

Chemerin and omentin-1 synthesis was dysregulated in MO patients. Chemerin might play a role in insulin resistance and oxidative stress. Chemerin changes seemed to be predicted mainly by insulin resistance. Omentin-1 levels were inversely associated with chronic inflammation and dyslipidemia while the main modulating factors seemed to be dyslipidemia, hyperglycemia and BMI.