Identifying hypoxic tissue after acute ischemic stroke using PET and ¹⁸ F-fluoromisonidazole

Abstract

PET with 18F-FMISO can detect peri-infarct hypoxic tissue after acute ischemic stroke. The distribution of hypoxic tissue suggests that it may represent the ischemic penumbra. Hypoxic tissues do not persist to the subacute phase of stroke (6 to 11 days).