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N-Heterocyclic carbene-catalyzed [4 + 1] annulation of phthalaldehyde and imines
36
Citations
78
References
2011
Year
Chemical EngineeringNovel OrganocatalystsEngineeringHeterocyclicDiastereoselective SynthesisOrganic ChemistryOrganometallic CatalysisCatalysisSynthetic ChemistryChemistryHeterocycle ChemistryStereoselective SynthesisAldol ReactionBiomolecular EngineeringTandem Aza-benzoin Reaction
The diastereoselective synthesis of cis-2-amino-3-hydroxyindanones was realized by the N-heterocyclic carbene-catalyzed [4 + 1] annulation of phthalaldehyde and imines, which may involve a tandem aza-benzoin reaction and aldol reaction.
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