A CONVENIENT SYNTHESIS OF SULFENYLATED ACTIVE METHYLENE COMPOUNDS USING DIARYL DISULFIDES

Abstract

Abstract A novel preparation of sulfenylated active methylene compounds has been investigated by the reaction of diaryl disulfides with active methylene compounds in a basic media. Malonates, acetoacetate, acetylacetone, and malononitrile gave selectively the corresponding monosulfenylated compounds at room temperature. At elevated temperatures, only malononitrile afforded a disulfenylated compound, while reactions with other active methylene compounds resulted in decomposition of the monosulfenylated products.