When<i>Z</i>‘ = 2 Is Better than<i>Z</i>‘ = 1Supramolecular Centrosymmetric Hydrogen-Bonded Dimers in Chiral Systems

Abstract

High Z‘ structures can be engineered by combining a molecule with one (or more) resolved chiral center(s) with a strongly directional supramolecular synthon with a preference for centrosymmetry because, in order to preserve the dimer motif, one or more extra molecules must be introduced into the asymmetric unit.