Cone-like Morphological, Molecular, and Electrophysiological Features of the Photoreceptors of the<i>Nrl</i>Knockout Mouse

Abstract

Many morphological, molecular, and electrophysiological features of the Nrl(-/-) photoreceptors are cone-like, and strongly distinguish these cells from rods. This retina provides a model for the investigation of cone function and cone-specific genetic disease.