Cell Surface Glycoconjugate Abnormalities and Corneal Epithelial Wound Healing in the<i>Pax6</i>^+/⁻Mouse Model of Aniridia-Related Keratopathy

Abstract

Alterations to the cell surface glycoconjugate signature of Pax6+/- corneal epithelia restrict the ability of cells to initiate migration in response to wounding. This underlies the observed wound-healing delay in cultured Pax6+/- epithelia.