The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission

Modafinil Binds to the Dopamine Uptake Carrier Site with Low Affinity

Emmanuel Mignot, Seiji Nishino, C. Guilleminault et al. · SLEEP · 1994 · 318 citations · Full text

Psychotropic Medication, Neurotransmitter, Pharmacotherapy +19

A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats

Jian‐Sheng Lin, Kazuya Sakai, Giovanna Vanni-Mercier et al. · Brain Research · 1989 · 315 citations

Neurobiological Mechanism, Neural Mechanism, Hypothalamus +13

The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain

Sergi Ferré, William T. O’Connor, Kjell Fuxé et al. · Journal of Neuroscience · 1993 · 254 citations · Full text

Synaptic Transmission, Neurotransmitter, Adenosine Antagonists +20

Long-lasting insomnia induced by preoptic neuron lesions and its transient reversal by muscimol injection into the posterior hypothalamus in the cat

M Sallanon, Michel Denoyer, Kunio Kitahama et al. · Neuroscience · 1989 · 230 citations

Long-lasting Insomnia, Sleep, Sleep Disorder +13

Central α1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals

J Duteil, Francis A. Rambert, J Pessonnier et al. · European Journal of Pharmacology · 1990 · 221 citations

Animal Physiology, Central α1-Adrenergic Stimulation, Neurophysiology +15