Treatment of HIV-related fluconazole-resistant oral candidosis with D0870, a new triazole antifungal

Abstract

D0870 shows promise in the treatment of fluconazole-resistant oro-oesophageal candidosis and was well tolerated, although efficacy in this difficult-to-treat patient group was probably limited due to the inadequate plasma levels achieved in this pilot study with the low doses of D0870 administered.