Proton conductance of human transient receptor potential–vanilloid type-1 expressed in oocytes of Xenopus laevis and in Chinese hamster ovary cells

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9K citations · Full text

Acute Pain, Pain Medicine, Anesthetic Mechanism +16

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

Makoto Tominaga, Michael J. Caterina, Annika B. Malmberg et al. · Neuron · 1998 · 3.1K citations · Full text

Health Sciences, Pain Medicine, Medicine +9

Acid potentiation of the capsaicin receptor determined by a key extracellular site

Sven‐Eric Jordt, Makoto Tominaga, David Julius · Proceedings of the National Academy of Sciences · 2000 · 637 citations · Full text

Molecular Pain, Vr1 Activation, Cellular Physiology +17

The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat

JM Welch, Sidney A. Simon, Peter H. Reinhart · Proceedings of the National Academy of Sciences · 2000 · 191 citations

Xenopus Laevis Oocytes, Activation Mechanism, Cellular Physiology +16

Agonist Recognition Sites in the Cytosolic Tails of Vanilloid Receptor 1

Jooyoung Jung, Soon-Youl Lee, Sun Wook Hwang et al. · Journal of Biological Chemistry · 2002 · 160 citations · Full text