Radiology · 1979 · 71 citations · 0 references
MedicineRadiologyVeterinary Diagnostic ImagingDiagnostic RadiologyHepatic PharmacokineticsHepatologyAdipose TissueComputed TomographyHepatic PathophysiologyLiver DiseaseLiver ImagingLiver PhysiologyCarbon Tetrachloride HepatotoxicityChemical-induced Fatty Liver DiseaseExperimental Study DesignFat Content MeasurementHepatic Lipid AccumulationHepatic Steatosis AssessmentHepatic Triglyceride MetabolismProtein Content Determination
The relation of liver fat content to CT number was studied in 20 rabbits (17 experimental, 3 control), where fatty degeneration was produced by carbon tetrachloride (CCl4) ingestion. Liver scanning was performed before and 2--5 days after CCl4 administration.. Changes (decrease) in CT number were compared with triglyceride (TG), water, and protein content of resected livers. A decrease of 12--20 CT numbers (24--40 H) reflected a TG concentration of 20--40 mg/g.