Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

Medicine, Pharmacology, Anesthesia +16

Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors

M. Kohlhardt, Benedikt Bauer, H. Krause et al. · Pflügers Archiv - European Journal of Physiology · 1972 · 597 citations

Natural Sciences, Cardiology, Physiology +17

A study of the ion selectivity and the kinetic properties of the calcium dependent slow inward current in mammalian cardiac muscle.

H. Réuter, Hasso Scholz · The Journal of Physiology · 1977 · 340 citations

Natural Sciences, Biophysics, Physiology +17

[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.

R J Gould, Kenneth M. Murphy, Solomon H. Snyder · Proceedings of the National Academy of Sciences · 1982 · 266 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?

J. Hescheler, D. Pelzer, G. Trube et al. · Pflügers Archiv - European Journal of Physiology · 1982 · 247 citations

Natural Sciences, Biophysics, Cardiology +12