Ca2+ as messenger of 5HT2-receptor stimulation in human blood platelets

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Sigmoidal Dose-response Curves, Physiologically-based Pharmacokinetic Modeling, Bioanalysis +21

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

Roger Y. Tsien, Tullio Pozzan, T J Rink · The Journal of Cell Biology · 1982 · 2.2K citations · Full text

Immunology, Molecular Biology, Cytoskeleton +20

A non-disruptive technique for loading calcium buffers and indicators into cells

Roger Y. Tsien · Nature · 1981 · 1.1K citations

Cell Physiology, In Vivo System, Membrane Transport +10

Enzyme changes in neonatal skeletal muscle: effect of thyroid deficiency

K. M. Baldwin, Antony M. Hooker, Patrick Campbell et al. · American Journal of Physiology-Cell Physiology · 1978 · 1.1K citations

Developmental Biology, Skeletal Muscle, Physiology +9

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Molecular Pharmacology, Molecular Neuroscience, Neurophysiology +12