Isochroman-6-carboxamides as Highly Selective 5-HT_1D Agonists: Potential New Treatment for Migraine without Cardiovascular Side Effects

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTIsochroman-6-carboxamides as Highly Selective 5-HT1D Agonists: Potential New Treatment for Migraine without Cardiovascular Side EffectsMichael D. Ennis, Nabil B. Ghazal, Robert L. Hoffman, Martin W. Smith, Siusaidh K. Schlachter, Charles F. Lawson, Wha Bin Im, Jeffrey F. Pregenzer, Kjell A. Svensson, Richard A. Lewis, Edward D. Hall, Dorothy M. Sutter, Lorri T. Harris, and Robert B. McCallView Author Information Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001 Cite this: J. Med. Chem. 1998, 41, 13, 2180–2183Publication Date (Web):June 3, 1998Publication History Received4 March 1998Published online3 June 1998Published inissue 1 June 1998https://pubs.acs.org/doi/10.1021/jm980137ohttps://doi.org/10.1021/jm980137orapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views781Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Agonists,Amides,Amines,Molecular structure,Receptors Get e-Alerts