Publication | Closed Access
Lipophilicity Determination of Some ACE Inhibitors by TLC
15
Citations
16
References
2008
Year
Medicinal ChemistryAce InhibitorsPharmaceutical SciencePharmacological StudyBiochemistryMedicineDrug DiscoveryNatural SciencesTlc Silica ParticlesAnalytical ChemistryChromatographic AnalysisPharmacologyPharmaceutical ChemistryChromatographyTlc Silica PlatesDrug Analysis
Abstract A simple and reliable reversed-phase TLC method was used to determine the lipophilicity of ACE inhibitors. The TLC silica plates were saturated with paraffin using continuous development with 10% paraffin in hexane for 18 hours. The TLC silica particles covered with the paraffin are used as an inexpensive substituent of the usual RP-18 TLC stationary phase.
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