In vitro and in vivo studies of temozolomide loading in zeolite structures as drug delivery systems for glioblastoma

Abstract

Y and MOR zeolites were used as a host for the temozolomide (TMZ). Y presented toxicity to glioblastoma cancer cells in contrast to MOR. Higher potentiation of TMZ was obtained with MOR in comparison to free TMZ both<italic>in vitro</italic>and<italic>in vivo</italic>.