A Preliminary Study of Fluvoxamine Maleate on Depressive State and Serum Melatonin Levels in Patients after Cerebral Infarction

Abstract

The administration of fluvoxamine to patients with depressive state after cerebral infarction alleviated both the depressive state and sleep disturbances. Increased melatonin levels by the administration of fluvoxamine may contribute to improvement in sleep disturbance, one of the major symptoms of depression.