Journal of the American Ceramic Society · 1992 · 515 citations · 24 references
Natural SciencesMaterials EngineeringMaterials ScienceBiomaterialsCeramic MaterialsCeramicsBioactive GlassesBioceramicsBone MineralizationBone TissueCementitious MaterialsCeramic BiomaterialsApatite Crystal GrowthApatite FormationApatite Layer FormationHydroxyapatite Crystal FormationMineral Phase CompositionSilica Gel Treatment
It has been confirmed that the essential condition for glasses and glass‐ceramics to bond to living bone is the formation of an apatite layer on their surfaces in the body. It has been proposed that a hydrated silica formed on the surfaces of these materials in the body plays an important role in forming the surface apatite layer, but this has not yet been proved. In the present study, it is shown experimentally that a pure hydrated silica gel can induce apatite formation on its surface in a simulated body fluid when its starting pH is increased from 7.2 to 7.4.
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Bioceramics: From Concept to Clinic
Larry L. Hench · Journal of the American Ceramic Society · 1991 · 4.9K citations
Natural Sciences, Bioengineering, Biomedical Engineering +16
Bioactive glass ceramics: properties and applications
Tadashi Kokubo · Biomaterials · 1991 · 1.2K citations
Natural Sciences, Materials Engineering, Materials Science +12