New Antimicrobial Substances against<i>Streptomyces scabies</i>from Rosemary (<i>Rosmarinus officinalis</i>L.)

Abstract

New antimicrobial substances against Streptomyces scabies, rosmic acid and rosmanol-related compounds, were isolated from leaves of rosemary (Rosmarinus officinalis L.). The active compounds were separated in pure form by a combination of gel permeation chromatography and reverse-phase HPLC. Their structures were determined by two-dimensional NMR experiments and HR-MS analyses.