TWO DIASTEREOISOMERIC α, β-DIAMINOBUTYRIC ACIDS FROM AMPHOMYCIN

Abstract

Acid hydrolysis of the peptide antibiotic amphomycinliberates a group of five basic amino acids. The major components of this mixture were isolated in pure form and identified as L, -threo-α, β-diaminobutyric acid and D-erythro-α, β-diaminobutyric acid. Both occur in the parent molecule. The basic amino acids present in minor amounts are also discussed.