Synthetic Routes towards Enantiomerically Pure β‐Amino Acids

Abstract

Unusual representatives of the synthetically attractive β-amino acids can be accessed by two novel synthetic routes. The synthesis of β2,3- and β2,3,3-amino acids (A and B, respectively) involves a diastereoselective 1,3-dipolar cycloaddition, whereas β2-amino acids C are obtained by enantioselective CuI-catalyzed conjugate addition of dialkyl zinc compounds to nitroalkenes.