Archives of Ophthalmology · 1987 · 13 citations · 1 references
Life SciencesGeneticsOphthalmologyHuman GeneticsMedical GeneticsPediatric OphthalmologyChromosomal DisordersCongenital DisordersCongenital Eye AnomaliesCongenital GlaucomaGenetic DisordersGlaucomaAutosomal Recessive InheritanceAutosomal TrisomyChromosome Banding PatternsChromosome Banding TechniquesCongenital Ocular DiseaseGenetic Causes Of GlaucomaGenetics Of Congenital GlaucomaOcular Congenital Anomalies
<h3>To the Editor.</h3> —With recent development of chromosome-banding techniques, several patients with congenital glaucoma due to a chromosomal abnormality have been described.<sup>1,2</sup>Though primary congenital glaucoma (PCG) has been considered to be an autosomal-recessive trait, clinical examinations have demonstrated that the glaucoma of such patients had the characteristics of PCG. We recently encountered a boy with both PCG and a chromosome abnormality. <h3>Report of a Case.</h3> —The patient, born at 42 weeks' gestation and weighing 3500 g, was the third child of healthy parents. He was first seen by us at 119 days of age. Intraocular pressure in each eye was 50.62 mm Hg, as measured by a Schiötz tonometer with the patient under anesthesia. The corneas of both eyes were hazy, with a rupture of Descemet's membrane. The horizontal and vertical diameters of the cornea were 13 mm and 12.5 mm, respectively, in each eye. Anterior chambers were
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