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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules

Jessica L. Childs‐Disney, Ewa Stępniak-Konieczna, Tuan Anh Tran, Ilyas Yildirim, HaJeung Park, Catherine Z. Chen, Jason W. Hoskins, Noel Southall, Juan Marugán, Samarjit Patnaik,

Nature Communications · 2013 · 95 citations · 42 references

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References

42

Myotonic Dystrophy Type 2 Caused by a CCTG Expansion in Intron 1 of <i>ZNF9</i>

Christina L. Liquori, K. Ricker, Melinda L. Moseley et al. · Science · 2001 · 1.2K citations

, , +9

Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy

Anne V. Philips, Lubov Timchenko, Thomas A. Cooper · Science · 1998 · 818 citations

, , +17

Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy

Rajesh S. Savkur, Anne V. Philips, Thomas A. Cooper · Nature Genetics · 2001 · 797 citations

, , +15

Expanded CUG Repeats Trigger Aberrant Splicing of ClC-1 Chloride Channel Pre-mRNA and Hyperexcitability of Skeletal Muscle in Myotonic Dystrophy

Ami Mankodi, Masanori Takahashi, Hong Jiang et al. · Molecular Cell · 2002 · 666 citations · Full text

, , +13

Loss of the Muscle-Specific Chloride Channel in Type 1 Myotonic Dystrophy Due to Misregulated Alternative Splicing

Rajesh S. Savkur, Gopal K. Singh, Anne V. Philips et al. · Molecular Cell · 2002 · 615 citations · Full text

, , +16