Interleukin‐6 is essential for Staphylococcal exotoxin B‐induced T regulatory cell insufficiency in nasal polyps

Abstract

SEB is able to modulate pro-inflammatory factors, T-helper type 1/Th2 profiles and suppress Treg activity in cultured nasal polyps, which were rescued by blocking IL-6 activity. Therefore, IL-6 is essential for SEB-induced Treg insufficiency in nasal polyps.