Successful treatment of premature rupture of membranes after genetic amniocentesis by intra‐amniotic injection of platelets and cryoprecipitate (amniopatch): a case report

Abstract

Intra-amniotic injection of platelets and cryoprecipitate was a successful and safe therapy for PROM in this patient. Knowledge of the site of rupture is not necessary for the amniopatch, as platelets seem to find their way to the defect and seal it. We consider that amniopatch therapy for iatrogenic PROM is a possible therapeutic alternative for prolonging and preserving pregnancy and improving the fetal outcome.