Concepedia

A rapid and sensitive method for determination of veliparib (ABT-888), in human plasma, bone marrow cells and supernatant by using LC/MS/MS

Sarah Reinhardt, Ming Zhao, Aleksander Mnatsakanyan, Linping Xu, Rebecca M. Ricklis, Alice P. Chen, Judith E. Karp, Michelle A. Rudek

Journal of Pharmaceutical and Biomedical Analysis · 2009 · 12 citations · 7 references

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References

7

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Cherrie K. Donawho, Yan Luo, Yanping Luo et al. · Clinical Cancer Research · 2007 · 773 citations · Full text

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Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies

Shivaani Kummar, Robert J. Kinders, Martin Gutierrez et al. · Journal of Clinical Oncology · 2009 · 329 citations · Full text

, , +16

Inhibition of Poly(ADP-Ribose) Polymerase Enhances Cell Death and Improves Tumor Growth Delay in Irradiated Lung Cancer Models

Jeffrey M. Albert, Carolyn Cao, Kwang Woon Kim et al. · Clinical Cancer Research · 2007 · 265 citations

, , +17

Plasma and cerebrospinal fluid pharmacokinetics of ABT-888 after oral administration in non-human primates

Jodi A. Muscal, Patrick A. Thompson, Vincent L. Giranda et al. · Cancer Chemotherapy and Pharmacology · 2009 · 34 citations · Full text

, , +11

Liquid chromatography–mass spectrometric assay for the quantitation in human plasma of ABT-888, an orally available, small molecule inhibitor of poly(ADP-ribose) polymerase

Robert A. Parise, Mohammad Shawaqfeh, Merrill J. Egorin et al. · Journal of Chromatography B · 2008 · 31 citations

, , +14