Spirogermanium: A new investigational drug of novel structure and lack of bone marrow toxicity

DRUG SENSITIVITY OF PLASMODIUM FALCIPARUM

Karl H. Rieckmann, Gary H. Campbell, L. J. Sax et al. · The Lancet · 1978 · 513 citations

Medicine, Pharmacology, Pharmacodynamics +9

Spirans XXII. Synthesis of 4,4‐dialkyl‐4‐germacyclohexanone and 8,8‐dialkyl‐8‐germaazaspiro [4.5] decanes

Leonard M. Rice, James W. Wheeler, Charles F. Geschickter · Journal of Heterocyclic Chemistry · 1974 · 45 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5

Cytotoxic effects and biological activity of 2-aza-8-germanspiro[4,5]-decane-2-propanamine-8,8-diethyl-N,N-dimethyl dichloride (NSC 192965; spirogermanium) in vitro.

Bridget T. Hill, S. A. Whatley, Angela S. Bellamy et al. · PubMed · 1982 · 41 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Phase I clinical trial of spirogermanium.

P S Schein, M Slavík, Tarilyn Smythe et al. · PubMed · 1981 · 37 citations

Medicine, Oncology, Pharmacology +13

Phase II trial of spirogermanium for treatment of advanced breast cancer.

Geoffrey Falkson, Falkson Hc · PubMed · 1983 · 24 citations

Medicine, Oncology, Breast Oncology +9