Diversity‐Oriented Synthesis of Useful Chiral Building Blocks from <scp>D</scp>‐Mannitol

Abstract

Abstract A diversity‐oriented synthesis is described for functionalized chiral building blocks (i.e., 7 , 9 , 10 , 16 , and 17 ) and the biologically active iminosugar, fucosidase inhibitor (2 S ,3 R ,4 R ,5 R )‐2‐(hydroxymethyl)‐5‐methylpyrrolidine‐3,4‐diol ( 22 ), starting from common chiral intermediate 1a which is obtained through a regioselective reductive cleavage of a bis(benzylidene) acetal.