Peroxynitrite-Induced Mitochondrial and Endonuclease-Mediated Nuclear DNA Damage in Acetaminophen Hepatotoxicity

DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

Sabine Jahr, Hannes Hentze, Susanne Englisch et al. · PubMed · 2001 · 2.2K citations

Life Sciences, Molecular Biology, Oncology +10

Sequence and gene organization of mouse mitochondrial DNA

Maureen J. Bibb, Richard A. Van Etten, C T Wright et al. · Cell · 1981 · 1.7K citations

Medicine, Genetics, Molecular Genetics +14

Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

Kazuyoshi Kon, Jae‐Sung Kim, Hartmut Jaeschke et al. · Hepatology · 2004 · 494 citations · Full text

Veterinary Medicine, Cell Biology, Pharmacology +17

Mode of Cell Death after Acetaminophen Overdose in Mice: Apoptosis or Oncotic Necrosis?

Jaspal Gujral · Toxicological Sciences · 2002 · 422 citations

Veterinary Medicine, Pharmacology, Toxicology +16

Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol.

Hartmut Jaeschke · Journal of Pharmacology and Experimental Therapeutics · 1990 · 334 citations

Veterinary Medicine, Pharmacology, Toxicology +17