Influence of surgical intervention in the immune response of severely injured patients

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

Jean‐Louis Vincent, Rui P. Moreno, Jukka Takala et al. · Intensive Care Medicine · 1996 · 11.2K citations

Viral Sepsis, Acute Care, Sepsis +4

Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma

Dorothee Decker, Martin Schöndorf, F. Bidlingmaier et al. · Surgery · 1996 · 386 citations

Inflammation, Surgical Stress, Autoimmune Disease +12

Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient

M J Hershman, William G. Cheadle, S R Wellhausen et al. · British journal of surgery · 1990 · 356 citations

Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery

C H Wakefield, P D Carey, S. Foulds et al. · British journal of surgery · 1993 · 258 citations

Histocompatibility, T-regulatory Cell, Immunology +18

Biochemical changes after trauma and skeletal surgery of the lower extremity: Quantification of the operative burden

Hans‐Christoph Pape, Reinhold E. Schmidt, John Jeremy Rice et al. · Critical Care Medicine · 2000 · 213 citations