Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies

Detecting Subtle Sequence Signals: a Gibbs Sampling Strategy for Multiple Alignment

Charles E. Lawrence, Stephen F. Altschul, Mark S. Boguski et al. · Science · 1993 · 1.8K citations

Life Sciences, Bioinformatics, Molecular Biology +17

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

Frank C. P. Holstege, Ezra G. Jennings, John J. Wyrick et al. · Cell · 1998 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Identifying DNA and protein patterns with statistically significant alignments of multiple sequences.

Gerald Z. Hertz, Gary D. Stormo · Bioinformatics · 1999 · 1.3K citations · Full text

Life Sciences, Bioinformatics, Biology +13

Extracting regulatory sites from the upstream region of yeast genes by computational analysis of oligonucleotide frequencies 1 1Edited by G. von Heijne

Jacques van Helden, Bruno André, Julio Collado‐Vides · Journal of Molecular Biology · 1998 · 750 citations

Life Sciences, Genetics, Molecular Biology +15

Introns increase transcriptional efficiency in transgenic mice.

Ralph L. Brinster, J M Allen, Richard R. Behringer et al. · Proceedings of the National Academy of Sciences · 1988 · 736 citations · Full text

Life Sciences, Genetics, Molecular Biology +16