Synthesis of Dialkyl 2‐(Alkylamino)‐4,9‐dihydro‐9‐oxocyclohepta[<i>b</i>]pyran‐3,4‐dicarboxylates

Abstract

Abstract Dialkyl 2‐(alkylamino)‐4,9‐dihydro‐9‐oxocyclohepta[ b ]pyran‐3,4‐dicarboxylates are prepared in a one‐pot three‐component reaction of alkyl isocyanide, dialkyl acetylenedicarboxylate, and α ‐tropolone (=2‐hydroxycyclohepta‐2,4,6‐trienone). The reaction proceeds smoothly at room temperature and under neutral conditions to afford tropolone derivatives in high yield.