Alterations of <b> <i>p16</i> </b> and Prognosis in Biliary Tract Cancers from a Population-Based Study in China

Abstract

Alteration of p16 gene alone or in combination with alterations of other tumor suppressor genes on chromosome 9p is a prognostic indicator in gallbladder carcinoma, with more favorable survival rates associated with carcinomas lacking p16 gene alterations.