New England Journal of Medicine · 2002 · 83 citations · 11 references
MedicineObstetricsSurgeryMaternal-fetal MedicineObstetric SurgeryPediatric NeurosurgeryFetal NeurosurgeryFetal SurgeryFetal TherapySpinal Cord InjuryCongenital Spinal AnomaliesCongenital Spinal Cord MalformationsDermoid Cyst ExcisionNeurologic DeficitsNeurologic Disorders In PregnancyPerinatal Neurosurgical ManagementPostnatal Surgical Repair
In utero surgery for myelomeningocele has been proposed to reduce neurologic dysfunction that may result from exposure of the spinal cord to amniotic fluid; approximately 220 such surgeries have been performed to date. The authors report on three girls under one year of age who had loss of motor function in the legs or loss of bladder function after in utero repair of myelomeningocele at 22 to 24 weeks of gestation. All three had dermoid cysts with associated spinal cord tethering, which required surgery.
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Fetal Surgery for Myelomeningocele and the Incidence of Shunt-Dependent Hydrocephalus
Joseph P. Bruner · JAMA · 1999 · 452 citations
Medicine, Pediatrics, Surgery +15
In utero surgery rescues neurological function at birth in sheep with spina bifida
Martin Meuli, Claudia Meuli‐Simmen, Grover M. Hutchins et al. · Nature Medicine · 1995 · 380 citations
Medicine, Obstetrics, Surgery +14
Endoscopic coverage of fetal myelomeningocele in utero
Joseph P. Bruner, William O. Richards, Noel Tulipan et al. · American Journal of Obstetrics and Gynecology · 1999 · 279 citations
Medicine, Obstetrics, Surgery +11