Expression of the Receptor Tyrosine Kinases, Epidermal Growth Factor Receptor, ErbB2, and ErbB3, in Human Ocular Surface Epithelia

Abstract

EGFR, ErbB2 and ErbB3 are expressed by the ocular surface epithelia. EGFR is preferentially expressed by the basal epithelial cells that have the greatest proliferative potential. In contrast, ErbB2 and ErbB3 are preferentially expressed by the superficial differentiated ocular surface epithelia.