Journal of Clinical Investigation · 1945 · 13 citations · 0 references
PharmacyInfectious DiseasesSurgeryAntimicrobial PharmacotherapyInfectious Disease PharmacotherapyPediatric Infectious DiseasesAntibacterial TherapyBacterial InfectionsPediatric Antibiotic TherapyDrainageFirst Rib ResectionOpen Surgical DrainagePneumococcal DiseasePneumococcal Pneumonia TreatmentPneumonia Antibiotic Therapy
In a previous article (1), results were presented concerning the use of penicillin, injected intra- pleurally, in the treatment of pneumococcal em- pyema. The method of treatment, its effect on the clinical course of the disease, and the final out- come were described in 8 patients. In 7 of them, the infection was eradicated and the suppurative process cleared completely without requiring more than repeated medical thoracenteses for drainage. In 1 patient, a child of 2 years of age, surgical drainage by rib resection was employed when a relapse of the infection occurred shortly after ces- sation of the first injections of penicillin.