Concepedia

Palladium-Catalyzed Direct Functionalization of Imidazolinone:  Synthesis of Dibromophakellstatin

Jianming Lü, Xianghui Tan, Chuo Chen

Journal of the American Chemical Society · 2007 · 93 citations · 41 references

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Abstract

The direct C−H functionalization of imidazolinone is achieved with Pd(OAc) 2 /NaOAc in DMSO. Dibromophakellstatin can be synthesized in five steps with 40% overall yield using this new C−H activation method.

References

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