Minocycline prevents the decrease in bone mineral density and trabecular bone in ovariectomized aged rats

Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

A. M. Parfitt, Catharina H. E. Mathews, A. R. Villanueva et al. · Journal of Clinical Investigation · 1983 · 1.5K citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

Robert L. Jilka, Giao Hangoc, Giuseppe Girasole et al. · Science · 1992 · 1.5K citations

Medicine, Endocrinology, Immunology +17

LONG-TERM PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS BY ŒSTROGEN

R. Lindsay, J. M. Aitken, L.B. Anderson et al. · The Lancet · 1976 · 956 citations

Medicine, Endocrinology, Preventive Medicine +9

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.

G. Girasole, R L Jilka, Giovanni Passeri et al. · Journal of Clinical Investigation · 1992 · 684 citations · Full text

Medicine, Endocrinology, Immunology +16

The Microanatomy of Trabecular Bone Loss in Normal Aging Men and Women

Jean E. Aaron, Naomi B. Makins, K Sagreiya · Clinical Orthopaedics and Related Research · 1987 · 424 citations

Medicine, Orthopedic Surgery, Surgery +12