Differential Involvement of Trigeminal Transition Zone and Laminated Subnucleus Caudalis in Orofacial Deep and Cutaneous Hyperalgesia: the Effects of Interleukin-10 and Glial Inhibitors

Abstract

These results support the hypothesis that the Vi/Vc transition zone is involved in deep orofacial injury and suggest that glial inhibition and interruption of the cytokine cascade after inflammation may provide pain relief.