A simple LC–MS/MS method for the determination of cortisol, cortisone and tetrahydro-metabolites in human urine: Assay development, validation and application in depression patients

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

Shuichi Chiba, Tadahiro Numakawa, Midori Ninomiya et al. · Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2012 · 674 citations

Life Sciences, Neurobiology, Neuroscience +17

Impaired Glucose Tolerance and Insulin Resistance Are Associated With Increased Adipose 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Elevated Hepatic 5α-Reductase Activity

Jeremy Tomlinson, Joanne Finney, Christopher Gay et al. · Diabetes · 2008 · 131 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Cortisol Metabolism in Depressed Patients and Healthy Controls

Benedikt Römer, S. Lewicka, Daniel Kopf et al. · Neuroendocrinology · 2009 · 61 citations

Medicine, Endocrinology, Psychiatry +17

11β-hydroxysteroid dehydrogenase type-2 and type-1 (11β-HSD2 and 11β-HSD1) and 5β-reductase activities in the pathogenia of essential hypertension

Carmen Campino, Cristián A. Carvajal, Javiera Cornejo et al. · Endocrine · 2009 · 45 citations · Full text

Life Sciences, Biochemistry, Cardiology +13

Simultaneous determination of tetrahydrocortisol, allotetrahydrocortisol and tetrahydrocortisone in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry

Kouwa Yamashita, Risa Nakagawa, Mitsunobu Okuyama et al. · Steroids · 2008 · 41 citations

Life Sciences, Biochemistry, Endocrinology +14