Downregulation of ATP-Binding Cassette Subfamily C Member 4 Increases Sensitivity to Neoadjuvant Radiotherapy for Locally Advanced Rectal Carcinoma

Abstract

Our data indicate that ATP-binding cassette subfamily C member 4 may be a useful molecular marker in predicting radiosensitivity, and a potential target in improving the response to neoadjuvant radiotherapy in locally advanced rectal carcinoma patients.