INTERLEUKIN-4 OR INTERLEUKIN-10 EXPRESSED FROM ADENOVIRUS-TRANSDUCED SYNGENEIC ISLET GRAFTS FAILS TO PREVENT ?? CELL DESTRUCTION IN DIABETIC NOD MICE1

Abstract

These results suggest that adenoviruses are efficient for at least medium term gene expression from islets in vivo, but neither IL-4 nor IL-10 alone can prevent autoimmune disease recurrence in NOD mice.