New Entry to γ-Butyrolactams by Free Radical Cyclization of <i>N</i>-Allyl-α-chloro-α-(methylthio)acetamides. Formal Total Synthesis of (±)-Pseudoheliotridane

Abstract

Abstract Tributyltin hydride-azobisisobutyronitrile induced radical cyclization of N-allyl-α-chloro-α-(methylthio)acetamides afforded γ-butyrolactams. This method was applied to the formal total synthesis of (±)-pseudoheliotridane.